氯乙酸甲酯

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2.对环境的影响:
一、健康危害

侵入途径：吸入、食入、经皮吸收。 
健康危害：吸入、食入、经皮吸收对身体有害。对眼睛、皮肤、粘膜和呼吸道有强烈的刺激性作用。吸入后可因喉、支气管的痉挛、水肿、化学性肺炎、肺水肿而致死。中毒表现有烧灼感、咳嗽、喘息、喉炎、气短、头痛、恶心、呕吐。

二、毒理学资料及环境行为

毒性：毒性比较大，对所有组织均有刺激作用。 
急性毒性：LD50240mg/kg(小鼠经口) ；LC501000mg/m3(小鼠吸入)

危险特性：易燃，遇明火、高热或与氧化剂接触，有引起燃烧爆炸的危险。受热、接触酸或酸雾放出剧毒的烟雾。 
燃烧(分解)产物：一氧化碳、二氧化碳、氯化氢。

迅速撤离泄漏污染区人员至安全区，并进行隔离，严格限制出入。建议应急处理人员戴自给正压式呼吸器，穿防毒服。不要直接接触泄漏物。防止进入下水道、排洪沟等限制性空间。小量泄漏：用砂土或其他不燃材料吸附或吸收。大量泄漏：构筑围堤或挖坑收容；用泡沫覆盖，降低蒸气灾害。用泵转移至槽车或专用收集器中，回收或运至废物处理场所处置。

二、防护措施

呼吸系统防护：可能接触其蒸气时，必须佩戴自吸过滤式防毒面具(全面罩)。紧急事态抢救或撤离时，佩戴氧气呼吸器。 
眼睛防护：呼吸系统防护中已作防护。 
身体防护：穿连衣式胶布防毒衣。 
手防护：戴橡胶手套。 
其它：工作现场禁止吸烟、进食和饮水。现场备有冲洗眼及皮肤的设备。工作毕，彻底清洗。单独存放被毒物污染的衣服，洗后备用。

三、急救措施

皮肤接触：立即脱去被污染的衣着，用大量流动清水冲洗，至少15分钟。就医。 
眼睛接触：立即提起眼睑，用大量流动清水或生理盐水彻底冲洗至少15分钟。就医。 
吸入：迅速脱离现场至空气新鲜处。保持呼吸道通畅。如呼吸困难，给输氧。如呼吸停止，立即进行人工呼吸。就医。 
食入：误服者用水漱口，给饮牛奶或蛋清。就医。

灭火方法：消防人员须佩戴防毒面具、穿全身消防服。喷水冷却容器，可能的话将容器从火场移至空旷处。灭火剂：雾状水、抗溶性泡沫、干粉、二氧化碳、砂土。用雾状水驱散蒸气。

CHEMICAL IDENTIFICATION

RTECS NUMBER :

AF9500000

CHEMICAL NAME :

Acetic acid, chloro-, methyl ester

CAS REGISTRY NUMBER :

96-34-4

LAST UPDATED :

199710

DATA ITEMS CITED :

9

MOLECULAR FORMULA :

C3-H5-Cl-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

250 ppm/7H

TOXIC EFFECTS :

Kidney, Ureter, Bladder - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :

TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 19,1,1971

TYPE OF TEST :

LD16 - Lethal Dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

560 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,82,1982

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

240 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,82,1982

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

1 gm/m3/2H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,82,1982

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - species unspecified

DOSE/DURATION :

240 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 39(4),86,1974 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4940 No. of Facilities: 22 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 1666 (estimated) No. of Female Employees: 272 (estimated)

67-56-1

甲醇

79-11-8

氯乙酸

~93%

96-34-4

6832-16-2

2-diazonio-1-me...

~93%

96-34-4

6832-16-2

2-diazonio-1-me...

292638-85-8

丙烯酸甲酯

~5%

19255-80-2

数据未登录

96-34-4

• 67-56-1
  甲醇
• 79-11-8
  氯乙酸
• 6832-16-2
  2-diazonio-1-me...
• 292638-85-8
  丙烯酸甲酯

• 54699-92-2
  4-甲基-1-哌嗪乙酸
• 52787-14-1
  4-甲酸甲酯苯乙酸甲酯
• 96125-49-4
  methanesulfonic...
• 42245-42-1
  3-(4-甲氧基苯基)环氧乙烷...