首先，将下载的安装文件zip包,http://www.mathworks.com/products/compiler/mcr/ MCR2013a
然后依次执行下面的命令：
进入目录：cd /tmp
解压缩：unzip MCR_R2012a_glnxa64_installer.zip -d MCR_R2012a_glnxa64_installer
进入子目录：cd MCR_R2012a_glnxa64_installer
安装：./install -mode silent -agreeToLicense yes
当出现下面的字样的时候，就表示MCR安装成功了：
Exiting with status 0
End – Successful.
Finished
然后提示需要设置环境变量
export MCR_HOME=/usr/local/MATLAB/MATLAB_Compiler_Runtime
export LD_LIBRARY_PATH=/usr/local/MATLAB/MATLAB_Compiler_Runtime/v81/runtime/glnxa64:/usr/local/MATLAB/MATLAB_Compiler_Runtime/v81/bin/glnxa64:/usr/local/MATLAB/MATLAB_Compiler_Runtime/v81/sys/os/glnxa64:/usr/local/MATLAB/MATLAB_Compiler_Runtime/v81/sys/java/jre/glnxa64/jre/lib/amd64/native_threads:/usr/local/MATLAB/MATLAB_Compiler_Runtime/v81/sys/java/jre/glnxa64/jre/lib/amd64/server:/usr/local/MATLAB/MATLAB_Compiler_Runtime/v81/sys/java/jre/glnxa64/jre/lib/amd64
export XAPPLRESDIR=/usr/local/MATLAB/MATLAB_Compiler_Runtime/v81/X11/app-defaults
下载mutsig安装包
运行
./run_MutSigCV.sh /usr/local/MATLAB/MATLAB_Compiler_Runtime/v81/ file.maf exome_full192.coverage.txt gene.covariates.txt test.txt mutation_type_dictionary_file.txt chr_files_hg19
测试完成即可。