INTRODUCTION TO BIOINFORMATICS
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=课程主页:http://ocw.metu.edu.tr/course/view.php?id=37,
Instructor: Tolga CAN
Added: 18 November 2009
Topic outline
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General
INTRODUCTION TO BIOINFORMATICS
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Topic 1
Introduction to Bioinformatics
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Topic 2
Introduction to biology, biological databases, and high-throughput data sources. Overview of bioinformatics problems.
Pairwise sequence alignment algorithms: Dynamic programming
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Topic 3
Statistical significance of alignments - Part I
Statistical significance of alignments - Part II
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Topic 4
Suffix Trees, Suffix Arrays
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Topic 5
Patterns, Profiles, and Multiple Alignments
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Topic 6
Hidden Markov Models
Week 5 Lecture Slides Continued
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Topic 7
Multiple Sequence Alignment Algorithms
Week 5 Lecture Slides Continued
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Topic 8
Midterm Review and Midterm Exam
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Phylogenetic trees
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Topic 9
Introduction to protein structures
Structure Prediction
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Topic 10
Protein Structure Prediction (continued)
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Topic 11
Protein Structure Prediction (continued)
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Topic 12
Structural Alignment of Proteins
(lecture notes continued) -
Topic 13
Microarray data normalization, analysis
Clustering techniques
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Topic 14
Introduction to Systems Biology
Gene regulatory networks
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Topic 15
Construction and Analysis of protein networks:
Monte Carlo Sampling, Random Walks on Graphs